Program in Molecular Biophysics > People

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Netz Arroyo

Associate Professor, Department of Pharmacology and Molecular Sciences

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Research Interests: Rational design of structure-switching nucleic acid aptamers for the development of electrochemical biosensors. Engineering of DNA-based hydrogels for environment-responsive therapeutic release.

Education: PhD, University of Texas at Austin

Scott Bailey

Associate Professor, Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health

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Research Interests: Structural and functional studies of protein-nucleic acid interaction

Education: PhD, University of Sheffield, UK

Doug Barrick (he)

Chair and Professor, Thomas C. Jenkins Department of Biophysics

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Research Interests: Stability and folding of modular proteins, structure and sequence analysis of protein evolution, protein-protein interactions in signaling pathways

Education: PhD, Stanford University

James Berger

Professor, Department of Biophysics and Biophysical Chemistry, School of Medicine

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Research Interests: Hybrid structural and functional studies of molecular machines; mechanisms of DNA replication, transcription, and chromosome organization; enzyme and small-molecule inhibitor mechanisms

Education: PhD, Harvard University

Gregory Bowman

Professor, Thomas C. Jenkins Department of Biophysics

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Research Interests: Structural biology, DNA-protein interactions

Education: PhD, Princeton University

Brian Camley

Assistant Professor, William H. Miller III Department of Physics & Astronomy

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Research Interests: Cell motility, chemotaxis, collective motion, soft matter, and fluid mechanics in cell biology

Education: PhD, University of California, Santa Barbara

Karen Fleming

Professor and PMB Director, Thomas C. Jenkins Department of Biophysics

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Research Interests: Membrane proteins, protein sorting, chaperone function, protein folding, thermodynamics of protein-protein interactions in membranes, membrane protein modeling

Education: PhD, Georgetown University

Stephen Fried (he/him/his)

Assistant Professor, Department of Chemistry

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Research Interests: Folding and assembly of proteins and molecular machines in vivo; crosslinking mass spectrometry; ancient proteins and the origins of life; synthetic biology and directed evolution.

Education: PhD, Stanford University

Dominique Frueh

Associate Professor, Department of Biophysics and Biophysical Chemistry, School of Medicine

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Research Interests: Use of nuclear magnetic resonance (NMR) to study modulations of protein dynamics and conformations in active enzymatic systems

Education: PhD, Ecole Polytechnique Fédérale de Lausanne (EPFL), Switzerland

Jeffrey Gray

Professor, Department of Chemical & Biomolecular Engineering, Whiting School of Engineering

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Research Interests: Protein structure prediction and design, protein-protein docking, antibody engineering, membrane protein modeling, glycoprotein modeling

Education: PhD, University of Texas, Austin

Rachel Green

Professor, Department of Molecular Biology and Genetics, School of Medicine

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Research Interests: In vitro selection approaches, mechanism of translation, ribosomal RNA (rRNA), ribosomes

Education: PhD, Harvard University

Vincent Hilser

Professor and Chair, Department of Biology

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Research Interests: Protein conformational fluctuations and their role in function, adaptation and disease

Education: PhD, Johns Hopkins University

Kalina Hristova

Professor, Department of Materials Science and Engineering, Whiting School of Engineering

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Research Interests: Cell signaling, membrane receptors, membrane cell biology, structure and function of membrane proteins, peptide–bilayer interactions, structure of membranes and lipid bilayers, membrane permeabilization, drug delivery, antimicrobial peptides

Education: PhD, Duke University

William Huang

Assistant Professor, Thomas C. Jenkins Department of Biophysics

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Research Interests: Physical principles of biochemical signaling; membrane signal transduction; single-molecule imaging, spectroscopy, and assays

Education: PhD, University of California, Berkeley

Margaret Johnson

Associate Professor, Thomas C. Jenkins Department of Biophysics

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Research Interests: Self-assembly and self-organization in cell biology. Clathrin-mediated endocytosis. Statistical mechanics, modeling dynamical systems.

Education: PhD, University of California, Berkeley

Jennifer Kavran

Associate Professor, Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health

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Research Interests: Biophysics, cell signaling, structural biology

Education: PhD, Yale University

Albert Lau

Associate Professor, Department of Biophysics and Biophysical Chemistry, School of Medicine

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Research Interests: Molecular mechanics of allostery and binding, structural biology, computational biophysics

Education: PhD, Harvard University

Chang Liu

Assistant Professor, Department of Biophysics and Biophysical Chemistry, School of Medicine

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Research Interests: Structural and molecular basis of virus-host interactions, mechanisms of viral and host gene regulation

Education: PhD, University of Minnesota, Twin Cities

Jian Liu

Associate Professor, Department of Cell Biology

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Research Interests: Theoretical modeling of how mechanics couples to biochemical reactions in defining spatial-temporal regulation over cell functions (i.e., cell migration, cell division and membrane traffic).

Education: PhD, University of California at Berkeley

Sean Prigge

Professor, Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health

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Research Interests: Enzymes and metabolic pathways in malaria parasites

Education: PhD, Johns Hopkins University

Steven Rokita

Professor, Department of Chemistry

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Research Interests: Bioorganic chemistry and biochemistry

Education: PhD, Massachusetts Institute of Technology

Jungsan Sohn

Associate Professor, Department of Biophysics and Biophysical Chemistry, School of Medicine

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Research Interests: Use of mechanistic enzymology and X-ray crystallography to study allosterically regulated biological stress-sensors

Education: PhD, Duke University

Jamie Spangler

Assistant Professor, Departments of Biomedical Engineering and Chemical & Biomolecular Engineering, Whiting School of Engineering

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Research Interests: Structural and molecular immunology, protein engineering, therapeutic antibody discovery and design, targeted drug development

Education: PhD, Massachusetts Institute of Technology

Edward Twomey

Assistant Professor, Department of Biophysics & Biophysical Chemistry

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Research Interests:  Structural and molecular mechanisms of neurotransmission and protein homeostasis

Education: Ph.D., Columbia University

Cynthia Wolberger

Professor and Director, Department of Biophysics and Biophysical Chemistry, School of Medicine

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Research Interests: Ubiquitin signaling, regulation of transcription, structural biology

Education: PhD, Harvard University

Sarah Woodson

Professor, Thomas C. Jenkins Department of Biophysics

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Research Interests: Folding and dynamics of RNA and RNA-protein complexes

Education: PhD, Yale University

Bin Wu

Assistant Professor, Department of Biophysics and Biophysical Chemistry, School of Medicine

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Research Interests: RNA biology, neuroscience, gene expression, single molecule imaging

Education: PhD, University of Minnesota, Twin Cities

Jie Xiao

Professor, Department of Biophysics and Biophysical Chemistry, School of Medicine

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Research Interests: Spatial organization and dynamics of chromosome and proteins, stochastic gene expression, cell division, superresolution imaging, and single-molecule biophysics

Education: PhD, Rice University

Yaojun Zhang

Assistant Professor, Department of Biophysics and Department of Physics and Astronomy

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Research Interests: Theoretical and computational biophysics, including single molecule mechanics, genome organization, intracellular transport, and biomolecular phase separation

Education: PhD, University of California, San Diego

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