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Enzymes & Metabolic Pathways

Barrick scientific imageDoug Barrick
Stability and folding of modular proteins, structure and sequence analysis of protein evolution, protein-protein interactions in signaling pathways
James Berger
Structure, mechanism, and regulation of molecular machines and assemblies
Bosch scientific imageJürgen Bosch
Assistant Professor
Structural biology of macromolecular complexes critical for malaria pathogenicity, structure-based drug design
Cole scientific image

Phil Cole
Chemical and biochemical approaches to signal transduction

Cone scientific imageRichard Cone
Mucosal protection by bacteria
Dominique Frueh research image

Dominique Frueh
Assistant Professor
NMR studies of modulations of protein dynamics and conformations in active enzymatic systems

Green scientific image

Rachel Green
Molecular mechanisms of translation and its regulation

Ostermeier scientific imageMarc Ostermeier
Biomolecular engineering
Prigge scientific imageSean Prigge
Associate Professor
Crystallography of malaria proteins
Roberts scientific imageElijah Roberts
Assistant Professor
Investigating the creation and use of in silico cell models
Steven Rokita research imageSteven Rokita
Mechanistic and structural studies of enzymes, reversible but covalent reactivity of nucleic acids
Roth scientific imageJustine Roth
Associate Professor
Metalloenzyme catalysis, mechanistic studies of oxidative protein modification and damage by reactive oxygen species
Jungsan Sohn research imageJungsan Sohn
Assistant Professor
Structure and function of biological stress-sensors
Jim Stivers research imageJim Stivers
Enzymology of DNA repair and topoisomerases, structure and mechanism by NMR spectroscopy, inhibitor design
Craig Townsend research imageCraig Townsend
Natural product chemistry, enzymology and molecular biology, fatty acid synthase inhibitors for cancer, tuberculosis and obesity
Cynthia Wolberger research imageCynthia Wolberger
Structural studies of transcription regulation, crystallography of transcriptional silencing enzymes, ubiquitin
Sarah Woodson research imageSarah Woodson
Folding and dynamics of RNA and RNA-protein complexes
Jin Zhang research imageJin Zhang
Associate Professor
Spatiotemporal regulation of signal transduction


Program in Molecular Biophysics
101 Jenkins Hall
3400 N. Charles Street
Baltimore, MD 21218

410-516-5197 phone
410-516-5199 fax


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