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Structural Biology

Amzel scientific imageMario Amzel
Structure and mechanism of proteins involved in redox or phosphoryl transfer reactions, such as FPPS, MICAL, and Pl3K-alpha.  Many of these proteins studied are targets for drug design.
James Berger
Structure, mechanism, and regulation of molecular machines and assemblies
Barrick scientific imageDoug Barrick
Stability and folding of modular proteins, structure and sequence analysis of protein evolution, protein-protein interactions in signaling pathways

Greg Bowman
Assistant Professor
Structural biology of molecular machines involved in nucleosome remodeling

Dominique Frueh
Assistant Professor
NMR studies of modulations of protein dynamics and conformations in active enzymatic systems

Albert Lau
Assistant Professor
Characterization of biomolecular association and conformational transitions using computational and crystallographic approaches

Juliette Lecomte
Structure and dynamics of protein in solution by NMR spectroscopy

Sean Prigge
Associate Professor
Crystallography of malaria proteins

Jungsan Sohn
Assistant Professor
Structure and function of biological stress-sensors

Schildbach scientific image

Joel Schildbach
Structural, biochemical, and functional studies of proteins involved in DNA transfer by bacterial conjugation

Herschel Wade
Assistant Professor
Molecular mechanisms of ligand-dependent transcriptional activation-repression, broadly-specific receptor-ligand systems
Joel Tolman research imageJoel Tolman
Associate Professor
Experimental and theoretical NMR, protein structure and function, polyubiquitylation
Scott Bailey
Assistant Professor
Structure/function studies of genome integrity
Cynthia Wolberger research imageCynthia Wolberger
Structural and mechanistic studies of transcription regulation and ubiquitin signaling


Program in Molecular Biophysics
101 Jenkins Hall
3400 N. Charles Street
Baltimore, MD 21218

410-516-5197 phone
410-516-5199 fax


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