New fields of scientific inquiry are emerging at a breathtaking pace. Biophysics, with its inherent foundation of integrative science, addresses the mysteries of life using all of the methods available to us through biology, biochemistry, chemistry, physics, engineering, and computer science.

Recent years have seen an explosion in biological information available to life science researchers. Hundreds of genomes have been sequenced and thousands of macromolecular structures have been determined. How do we make sense of this information? How do we organize it to broaden our understanding?

With advances in computational power and sophisticated instrumentation, we are now in a position to develop a comprehensive view of the molecular basis of life.

PMB faculty and the student researchers in their laboratories apply a wide range of approaches in their search for fundamental principles underlying the many reactions and interactions in living systems.

What Is Molecular Biophysics?

The goal of molecular biophysics is to explain biological phenomena in terms of the physical and chemical properties of participating ions and molecules.

This rapidly evolving field draws from the rich interactions that have developed among the traditional areas of chemistry, biology, physics, genetics, computer science, and others.

The Program in Molecular Biophysics is a PhD program for students who are interested in the integration of diverse disciplines toward greater understanding of living matter.

Researchers in the program combine the power of modern spectroscopic methods and computational approaches to unravel the determinants of self-assembly in biological systems.

Others use the tools of chemistry and structural biology to probe the physical bases for molecular recognition and guide the design of new and better drugs to treat debilitating diseases.

Still others focus on fundamental aspects of solution thermodynamics and refine the description of biological macromolecules in their cellular environment.

The curriculum of the Program in Molecular Biophysics is designed to expose students to fundamental aspects of biomolecular structure, energetics, and dynamics, and to provide practical experience in computational analysis. The courses and seminars build the conceptual framework necessary for expanding the borders of biophysical knowledge.