In addition to access to specialized instrumentation in individual labs, students have access to the following university-wide core facilities:
CMB has instrumentation for solution biophysics including absorbance, fluorescence, and circular dichroism spectroscopy, analytical ultracentrifugation, and isothermal and scanning calorimetry. Students receive hands-on training from Dr. Katie Tripp, director of the center.
Located in the Department of Biophysics and Biophysical Chemistry at the School of Medicine, this facility is fully equipped with several X-ray generators, detectors, and computers. It is maintained as a departmental facility and staffed by a full-time manager.
A structural analysis center in the New Chemistry Building on the Homewood campus.
Located in the School of Medicine, this facility houses a state-of-the-art Titan Krios microscope, and provides training for data collection and analysis.
State-of-the-art solution state NMR including 500, 600, and 800 MHz-NMR spectrometers. In-depth training is provided by Dr. Ananya Majumdar, director of the center.
Accurate mass measurements for small and large molecules can be obtained at the Mass Spectrometry Facility of the Chemistry Department and the Proteomics Facility of the Institute for Basic Biomedical Sciences.
An advanced supercomputing center located on the Hopkins Bayview Campus with over 23,000 cores with a combined performance of 1.4 PFLOPs.
Synthesis and Sequencing
Protein and nucleic acids can be made or analyzed with excellent turn-around time at the Synthesis and Sequencing Facility of the School of Medicine.
Facilities in the Community
The Biophysics Core Facility supports Johns Hopkins Malaria Research Institute investigators who want to characterize macromolecules or macromolecular complexes using biophysical techniques (isothermal titration calorimetry, dynamic light scattering, circular dichroism, and x-ray crystallography).
Basic and advanced light and electron microscopy (LM/EM), including 3-D and 4-D imaging, FRET, FRAP, and FCS, among others.
Advanced microscopy including confocal fluorescence, electron, lattice light-sheet and two-photon microscopy.
Compound repository and high throughput robotics laboratory services for enzymatic and biologic assays.
For the characterization and separation of particles as diverse as beads, cells, and chromosomes.